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作者: 編輯:李貴葉-康健學院 審核人: 宣布时间:2025-04-24 14:54 來源: 點擊量:

個人簡介

副教授,孔雀人才

研究偏向:微納米制備生物醫學工程器件、納米醫藥、藥物遞送

教育及事情經曆:

2010年四川大學,生物醫學工程專業,本科;2011-2015年,香港都市大學,超金剛石與先進薄膜中心(COSDAF)獲得博士學位;先後任職于成都大學、國藥集團四川抗菌素工業研究所以及澳大利亞蒙納士大學藥學院;于2020年入職深圳技術大學,康健與環境工程學院,任助理教授;于2022年12月晉升爲副教授。

主持或參與的基金項目:

1、國家自然科學基金青年基金;

2、深圳市高層次引進人才啓動項目。

代表著作:

1Yan L., Chen X. Chapter 7 - Nanomaterials for Drug Delivery. In SC Tjong (ed.), Nanocrystalline Materials (Second Edition) Oxford: Elsevier; 2014. p. 221-268.

代表專利:

1Yan L. and Chen X., Mechanically robust fast-dissolving microneedles for transdermal drug and vaccine delivery. US Patent 9526884, published on 27 Dec 2016. PRC Patent, CN 201310573710.

代表文章:

1Yan L., Gopal A., Kashif S., Hazelton P., Lan M.H.*, Zhang W.J.*, Chen X.F.* Metal organic frameworks for antibacterial applications. Chemical Engineering Journal, 2022, 435, 134975.

2Liu J.X.#, Yan L.#, He S.L., Hu J.* Engineering DNA quadruplexes in DNA nanostructures for biosensor construction. Nano Research, 2022, 15, 3504.

3Yan L.*, Li J., Gopal A., Roberts S.C., Lin J.F., Liu T.T., Munshi T., Zhang X.J., Chen X.F. Layered double hydroxides-silver-chlorin e6 nanocomposite for photo-chemo combination therapy to efficiently combat both Gram-positive and Gram-negative bacteria. Mater. Today Commun., 2022, 30, 103101.

4Zhao S.,# Yan L.,# Cao M.,# Huang L., Yang K., Wu S., Lan M.,* Niu G., Zhang W.J.* Near-Infrared Light-Triggered Lysosome-Targetable Carbon Dots for Photothermal Therapy of Cancer. ACS Applied Materials & Interfaces 2021, 13, 53610-53617.

5Peng X., Ai F., Yan L.*, Ha E., Hu X., He S., Hu J.* Doped inorganic semiconductor nanocrystals: synthesis strategies and biomedical applications. Cell Reports Physical Science, 2021, 2, 100436.

6Chen Y., Gao M., Zhang L., Ha E., Hu X., Zou R.*, Yan L.*, Hu J.* Tumor Microenvironment responsive biodegradable Fe-Doped MoOx nanowires for magnetic resonance imaging guided photothermal enhanced chemodynamic synergistic antitumor therapy. Advanced Healthcare Materials, 2021, 2001665.

7Li J., Gopal A., Karaosmanoglu S., Lin J., Munshi T., Zhang W.,* Chen X.,* Yan L.* Photosensitizer doped zeolitic imidazolate framework-8 nanocomposites for combined antibacterial therapy to overcome methicillin-resistant Staphylococcus aureus (MRSA). Colloid and Surfaces B: Biointerfaces 2020, 110900.

8Yan L., Alba M.,* Tabassum N., Voelcker N.H.* Micro- and nanosystems for advanced transdermal delivery. Advanced Therapeutics 2019, 201900141.

9Yan L., Gonca S., Zhu G., Zhang W., Chen X.* Layered double hydroxide nanostructures and nanocomposites for biomedical applications. Journal of Materials Chemistry B 2019, 5583-5601.

10Lin J., Li J., Gopal A., Munshi T., Chu Y., Wang J., Liu T., Shi B., Chen X.*, Yan L.* Synthesis of photo-excited Chlorin e6 conjugated silica nanoparticles for enhanced anti-bacterial efficiency to overcome methicillin-resistant Staphylococcus aureus. Chemical Communications 2019; 55:2656-2659.

11Yan L., Zhou M., Zhang X., Huang L., Chen W., Roy V.A.L., Zhang W., Chen X. A novel type of aqueous dispersible ultrathin layered double hydroxide nanosheets for in vivo bioimaging and drug delivery. ACS Applied Materials & Interfaces 2017; 9:34185-34193.

12Yan L., Chen X., Wang Z., Zhang X., Zhu X., Zhou M., Chen W., Huang L., Roy V.A.L., Yu P.K.N., Zhu G., Zhang W. Size controllable and surface tunable zeolitic imidazolate framework-8 (ZIF-8)-poly(acrylic acid sodium salt) (PAAS) nanocomposites for pH responsive frug release and enhanced in vivo cancer treatment. ACS Applied Materials & Interfaces 2017; 9:32990-33000.

13Yan L., Wang Z., Chen X., Guo X., Zhang Z., Zhu X., Lan M., Chen W., Zhu G., Zhang W. Firmly anchored photosensitizer Chlorin e6 to layered double hydroxide nanoflakes for highly efficient photodynamic therapy in vivo. Chemical Communications 2017; 53: 2339-2342.

14Yan L., Yang Y., Zhang W., Chen X. Advanced materials and nanotechnology for drug delivery. Advanced Materials 2014; 26:5533-5540.

15Yan L., Raphael A.P., Zhu X., Wang B., Chen W., Tang T., Deng Y., Sant H.J., Zhu G., Choy K.W., Gale B.K., Prow T., Chen X. Nanocomposite-strengthened dissolving microneedles for improved transdermal delivery to human skin. Advanced Healthcare Materials 2014; 3:555-564.

16Yan L., Zhang J., Lee C., Chen X. Micro- and nanotechnologies for intracellular delivery. Small 2014; 10:4487-4504.

17Yan L., Wang Y., Li J., Kalytchuk S., Susha A.S., Kershaw S.V., Yan Feng, Rogach A.L., Chen X. Highly luminescent covalently bonded double hydroxide nanoparticle-fluorescent dye nanohybrids. Journal of Materials Chemistry C 2014; 2:4490-4494.

18Yan L., Chen W., Zhu X., Huang L., Wang Z., Zhu G., Roy V.A.L., Chen X. Folic acid conjugated self-assembled layered double hydroxide nanoparticles for high-efficacy-targeted drug delivery. Chemical Communications 2013; 49(93):10938-10940.

聯系方式:yanli@ffjwd.com

 

 

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